Transcriptomics

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Effect of MEL-18 knockdown on estrogen-sensitive MCF7 breast cancer cells


ABSTRACT: Gene expression analysis of MEL-18-silenced MCF7 cell lines. MEL-18 is a component of the polycomb repressive complex (PRC)-1, which is a critical epigenetic modulator of stem cell regulation and normal and cancerous development. Accumulating studies have suggested that MEL-18 might act as a tumor suppressor in several human tumors, including breast cancer. Results provide insight into the functional role of MEL-18 in estrogen-dependent breast cancer.

ORGANISM(S): Homo sapiens

PROVIDER: GSE64716 | GEO | 2015/05/01

SECONDARY ACCESSION(S): PRJNA271730

REPOSITORIES: GEO

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