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Response to SARS-CoV in the PreCC

ABSTRACT: In order to narrow candidate QTL loci into relevant genes driving disease differences, we assessed transcriptional differences across the pre-CC population used to map phenotypic QTL. We integrate this normalized expression data with polymorphisms underneath a candidate locus to arrive at a high priority candidate gene which had genetic variants private to the causal haplotype and also had expression strongly correlated with the appropriate trait (SARS-CoV viral lung load at 4 DPI).

ORGANISM(S): Mus musculus

PROVIDER: GSE93283 | GEO | 2017/03/31

SECONDARY ACCESSION(S): PRJNA360460

REPOSITORIES: GEO

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