Transcriptomics

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Studying iPSCs from a hibernating mammal reveals molecular mechanisms of cold resistance in neural tissues


ABSTRACT: To explore the cold resistant feature of ground squirrel neuron cells, we compared transcriptomes of human and ground squirrel iPSC derived neurons in the response to cold treatment. We identified several key pathways that are critical for the maintenance of neuronal microtubule cytoskeleton integrity at low temperature.

OTHER RELATED OMICS DATASETS IN: PRJNA362861

ORGANISM(S): Ictidomys tridecemlineatus Homo sapiens

PROVIDER: GSE93935 | GEO | 2018/03/22

REPOSITORIES: GEO

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