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MiRNA expression data from fractionated SH-SY5Y cells

ABSTRACT: miRNA activity is typically associated with the cytoplasm, but a growing body of evidence suggests non-canonical roles for miRNA in the nucleus. We study miRNA dynamics in neurons and wanted to investigate this possibility in a human neuronal model. We used microarrays to investigate the miRNA composition of the nuclear and cytoplasmic compartments of undifferentiated SH-SY5Y cells.

ORGANISM(S): synthetic construct Homo sapiens

PROVIDER: GSE94483 | GEO | 2017/12/01

SECONDARY ACCESSION(S): PRJNA369856

REPOSITORIES: GEO

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Expression data from fractionated SH-SY5Y cells

Project description:miRNA activity is typically associated with the cytoplasm, but a growing body of evidence suggests non-canonical roles for miRNA in the nucleus. We study miRNA dynamics in neurons and wanted to investigate this possibility in a human neuronal model. We used microarrays to investigate the miRNA and mRNA composition of the nuclear and cytoplasmic compartments of undifferentiated SH-SY5Y cells to identify miRNA-target relationships and networks.

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miRNA profiling in HEV71-infected SH-SY5Y cells

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Gene expression during neuronal differentiation in two subtypes of SH-SY5Y

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