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Analysis of microRNA expression profiles in Xp11 renal cell carcinoma compared to normal adjacent tissue.

ABSTRACT: Renal cell carcinomas (RCCs) with Xp11 translocation (Xp11 RCC) constitute a distinctive molecular subtype characterized by chromosomal translocations involving the Xp11.2 locus, resulting in gene fusions between the TFE3 transcription factor with a second gene (usually ASPSCR1, PRCC, NONO, or SFPQ). RCCs with Xp11 translocations comprise up to 1-4% of adult cases, frequently displaying papillary architecture with epithelioid clear cells.

ORGANISM(S): Homo sapiens

PROVIDER: GSE95384 | GEO | 2017/04/27

SECONDARY ACCESSION(S): PRJNA377086

REPOSITORIES: GEO

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