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Global miRNA expression profile in cardiac progenitor cells generated by ISX-9

ABSTRACT: We developed a strategy to generate cardiac progenitor cells from human induced pluripotent stem cells using a novel small molecule.miRNA-sequencing results showed different miRNA expression profile among undifferentiated human induced pluripotent stem cells(hiPSCs), DMSO and ISX-9 treated hiPSCs.In comparsion with DMSO treated cells, ISX-9 upregulated several myogenic miRNAs and cardiac hypertrophy related-miRNAs including miR-335, miR-21, miR-30c,miRNA-181a and miR-214.

ORGANISM(S): Homo sapiens

PROVIDER: GSE95390 | GEO | 2017/12/30

SECONDARY ACCESSION(S): PRJNA376872

REPOSITORIES: GEO

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Global mRNA expression profile in cardiac progenitor cells generated by ISX-9

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