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H3K4ox-Mediated Chromatin Condensation Protects Breast Cancer Cells from the DNA Damage Repair Machinery

ABSTRACT: Using an H3K4ox-specific antibody, we determined that the H3K4ox modification is enriched in triple-negative breast cancer (TNBC) cells compared with luminal breast cancer subtypes—correlating with high LOXL2 levels— and, importantly, is found primarily in heterochromatin.

ORGANISM(S): Homo sapiens

PROVIDER: GSE96064 | GEO | 2019/03/06

REPOSITORIES: GEO

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