Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Metabolic pathways-associated lncRNA expression profiles of 6 human samples derived from patients with gastric cancer

ABSTRACT: Detection and analysis of metabolism pathway related to lncRNAs expression profile in gastric cancer.

ORGANISM(S): Homo sapiens

PROVIDER: GSE96856 | GEO | 2018/05/09

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

LncRNA expression profiles for 6 human samples derived from patients with gastric cancer

Project description:Investigation of lncRNA expression profile of gastric cancer A six chip study using total RNA extracted from three gastric cancer tissues and three paracancerous tissues

2013-06-12 | E-GEOD-47850 | biostudies-arrayexpress

LncRNA expression profiles for 6 human samples derived from patients with gastric cancer

Project description:Investigation of lncRNA expression profile of gastric cancer

2013-06-12 | GSE47850 | GEO

LncRNA-miRNA-mRNA network interactions with clinicopathological outcomes in gastric cancer patients

Project description:To investigate lncRNA-miRNA-mRNA network interactions with clinicopathological outcomes in gastric cancer, microarray analysis was obtained by microRNA profiling from the patient samples. The potential target genes were then predicted by miRmap, targetscan, and miRWalk2.0. The candidate lncRNAs were collected by the LncRNA2target and TANRIC databases. The expression levels of candidate lncRNAs, miRNAs, and mRNAs were measured in tumor and normal samples using qRT-PCR and ELIZA techniques and compared with the clinicopathological outcomes. We then performed gene expression profiling analysis using data obtained from RNA-seq of two tissue samples of gastric cancer patients.

2022-07-02 | GSE207154 | GEO

Long noncoding RNA profiles in plasma exosomes of patients with gastric high-grade intraepithelial neoplasia

Project description:The sensitivity and specificity of traditional non-invasive diagnostic markers for gastric cancer are insufficient. Long-chain noncoding RNAs (lncRNAs) in circulating exosomes are a new class of promising cancer biomarkers. However, the expression profile of long-chain noncoding RNAs (lncRNAs) in exosomes derived from gastric high-grade intraepithelial neoplasia (GHGIN) has not been reported.The aim of this study was to investigate the expression profile of long non-coding RNAs (lncRNAs) in the plasma exosomes of patients with gastric high-grade intraepithelial neoplasia. Peripheral blood samples were collected from five patients with GHGIN and five healthy donors, and the exosomes were isolated. We used high-throughput sequencing to detect differently expressed lncRNAs (DE lncRNAs) in these individuals. Real-time quantitative polymerase chain reaction (RT-qPCR) assay was performed to verify the sequencing results. The potential roles of the DE lncRNAs in GHGIN were speculated by performing Gene ontology (GO) and Kyoto Encyclopedia of Gene and Genome (KEGG) analysis. We constructed a lncRNAs–miRNA–mRNA network diagram and performed association analyses to explore the underlying molecular mechanisms. A total of 25145 lncRNAs were identified in all samples; 83 lncRNAs that showed significant differential expression were further screened, including 76 up‐regulated and 7 down‐regulated lncRNAs. RT-qPCR further confirmed these results. GO and KEGG analyses predicted that these lncRNAs played important roles in protein and macromolecule glycosylation, regulation of protein ubiquitination, and renin-angiotensin system and MAPK signaling pathways. We further constructed a lncRNA–miRNA–mRNA interaction network. This study may help in discovering new molecular changes, enrich the expression profile of lncRNAs in human GHGIN, and help us better understand the molecular mechanisms of GHGIN and gastric cancer.

2020-06-29 | GSE153413 | GEO

LncRNA expression profile in gastric cancer specimens and adjacent noncancerous tissues

Project description:We implemented lncRNA microarray analysis in 5 paired gastric cancer tissues and adjacent noncancerous tissues to identify differential expression of lncRNAs and mRNAs in gastric cancer.

2021-04-14 | GSE157289 | GEO

CircRNA expression profiles for 6 human samples derived from patients with gastric cancer

Project description:Investigation of circRNA expression profile of gastric cancer

2017-01-01 | GSE89143 | GEO

CircRNA expression profiles for 6 human plasma samples derived from patients with gastric cancer

Project description:Investigation of circRNA expression profile of gastric cancer

2017-01-14 | GSE93541 | GEO

Gastric cancer samples of Mexican patients

Project description:Cancer Gastric (CG) is a multifactorial disease with an important genetics background, per example copy number variants (CNV). Microarray data analysis were performed to identify CNV that could be contributing to those Mexican patient's clinical phenotypes

2022-04-13 | GSE117093 | GEO

identification of differentially expressed Long Non-coding RNA profiles in advanced gastric cancer

Project description:Long non-coding RNAs (lncRNAs) may contribute to tumorigenesis and cancer progression by regulating the gene in various cancers, including advanced gastric cancer (AGC). To investigate differentially expressed lncRNAs in AGC, we use whole transcriptome sequencing in 3 pairs of human gastric adenocarcinoma and the corresponding normal tissues.

2023-08-10 | GSE210909 | GEO

Gastric cancer samples of Mexican patients

Project description:Gastric cancer samples of Mexican patients

| PRJNA481039 | ENA