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Open chromatin in somatic cells transplanted into Xenopus oocytes

ABSTRACT: Active gene transcription is associated with an open chromatin configuration at gene regulatory regions. However, the relationship between chromatin architecture of somatic cells and transcriptional activation during nuclear reprogramming in oocytes is unclear. We therefore examined changes in open chromatin states before and after transplantation of mouse somatic nuclei into Xenopus laevis oocytes by using the Assay for Transposase-Accessible Chromatin Sequencing (ATAC-seq).

ORGANISM(S): Mus musculus musculus x Mus musculus castaneus Mus musculus

PROVIDER: GSE98776 | GEO | 2018/07/10

REPOSITORIES: GEO

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