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H3K36me3 protects the mouse epigenome from single nucleotide variations [mRNA-Seq]

ABSTRACT: The goals of this project are to study the transcriptome profiling (RNA-seq) of mouse embryonic stem cells by histone mutants incorporation (H3.1K3M, H3.1K36M vs H3.1wt) or shRNA-mediated knockdown of methyl-transferase Suv39h1/h2 (shSuv39h1, shSuv39h2 vs shNC)

ORGANISM(S): Mus musculus

PROVIDER: GSE99155 | GEO | 2019/08/01

REPOSITORIES: GEO

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H3K36me3 protects the mouse epigenome from single nucleotide variations

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