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Human AsPC1-CFP and AsPC1-AKT PDAC orthotopic tumors: Lean vs Obese

ABSTRACT: Transcriptional profiling comparing human AsPC1 PDA cells transduced with either CFP control or myristoylated-AKT orthotopically grown in pancreata of lean vs obese Rag1-/- immunodeficient mice for 5 weeks (100,000 cells/pancreas). The Goal was to determine the transcriptional deregulation of Obesity-driven and AKT-driven tumors.

ORGANISM(S): Homo sapiens

PROVIDER: GSE99289 | GEO | 2017/05/26

SECONDARY ACCESSION(S): PRJNA388041

REPOSITORIES: GEO

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Homo sapiens

Project description:Human AsPC1-CFP and AsPC1-AKT PDAC orthotopic tumors: Lean vs Obese

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Expression data from isogenic Pten WT mouse T-ALLs infected with MSCV Myr-AKT-IRES-mCherry or empty vector, treated with DBZ or DMSO

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Expression data from AsPC1 cells treated with ICG-001

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