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Expression data from AsPC1 cells treated with ICG-001

ABSTRACT: The CREB binding protein inhibitor ICG-001 suppresses pancreatic cancer growth We used microarrays to detail global gene expression changes in the pancreatic cancer cell line AsPC1 following treatment with ICG-001 or siRNA-mediated knockdown of CTNNB1 (beta-catenin)

ORGANISM(S): Homo sapiens

PROVIDER: GSE57728 | GEO | 2014/07/15

SECONDARY ACCESSION(S): PRJNA247965

REPOSITORIES: GEO

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Expression data from AsPC1 cells treated with ICG-001

Project description:The CREB binding protein inhibitor ICG-001 suppresses pancreatic cancer growth We used microarrays to detail global gene expression changes in the pancreatic cancer cell line AsPC1 following treatment with ICG-001 or siRNA-mediated knockdown of CTNNB1 (beta-catenin) AsPC1 cells were treated with 10uM ICG-001 or vehicle control (DMSO) for either 6 hours or 24 hours. AsPC-1 cells were also separately transfected with 20nM control siRNA or CTNNB1 siRNA for 48 hours. RNA was extracted at these time points for hybridization to Affymetrix microarrays

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Expression data from AsPC1 cells treated with ICG-001

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Altering cancer transcriptomes using epigenomic inhibitors [Illumina beadchip]

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