Project description:Despite the importance and wide exploitation of heterosis in commercial crop breeding, the molecular mechanisms behind this phenomenon are not completely understood. In this study we aimed to understand and quantify the contribution of DNA methylation variation to heterosis in various traits of Arabidopsis. Therefore we created epigenetic hybrid lines from ddm1-derived epiRILs. We performed RNA sequencing on four epiHybrids and their parental lines (epiRILs & Col-wt) in duplicates/triplicates to understand gene expression changes in hybrids genome wide and with a focus on previously mapped QTL regions.

2017-12-07 | GSE99405 | GEO

Genome-wide DNA methylation profiles from Arabidopsis epiRILs, epiHybrids and Colombia wild type

Project description:Despite the importance and wide exploitation of heterosis in commercial crop breeding, the molecular mechanisms behind this phenomenon are not completely understood. In this study we aimed to understand and quantify the contribution of DNA methylation variation to heterosis in various traits of Arabidopsis. Therefore we created epigenetic hybrid lines from ddm1-derived epiRILs. We performed whole genome bisulfite sequencing on four epiHybrids and their parental lines (epiRILs & Col-wt) in duplicates to understand methylome remodelling in hybrids genome wide and with a focus on previously mapped QTL regions.

2017-12-07 | GSE99404 | GEO

Microarray and ChIP-chip of Rrm3-Flag in wild-type and npl3 cells, and ChIP-chip of Npl3-Myc in wild type cells

Project description:This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

2013-11-15 | E-GEOD-50187 | biostudies-arrayexpress

Gene expression pattern between Wild-type and Setd2 knockout mESCs

Project description:This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

2014-10-14 | E-GEOD-54933 | biostudies-arrayexpress