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NG Capture-C analysis of GADD45a-bound adipogenic super-enhancers

ABSTRACT: ING1b and GADD45a are nuclear proteins involved in the regulation of cell growth, apoptosis and DNA repair. We previously found that ING1b is essential to target GADD45a-mediated active DNA-demethylation via TET1 to specific loci. In order to study the physical interaction of distant GADD45a and ING1 bound regions, we performed multiplexed NG Capture-C chromatin conformation capture assay in wildtype and knockout mouse embryonic fibroblasts.

ORGANISM(S): Mus musculus

PROVIDER: GSE99606 | GEO | 2018/06/11

REPOSITORIES: GEO

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