Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

GNPS - 20240105 ISS standard validation positive

ABSTRACT: Standard validation for annotations from space station surface

INSTRUMENT(S): Q Exactive

ORGANISM(S): Na

SUBMITTER: Pieter C. Dorrestein

PROVIDER: MSV000093781 | GNPS | Fri Jan 05 17:12:00 GMT 2024

REPOSITORIES: GNPS

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

20240105 ISS standard validation positive

Project description:Standard validation for annotations from space station surface

2024-01-05 | MSV000093781 | MassIVE

20240105 ISS standard validation negative ionization

Project description:Standard validation of annotations from space station surfaces, negative ionization

2024-01-05 | MSV000093782 | MassIVE

GNPS - 20240105 ISS standard validation negative ionization

Project description:Standard validation of annotations from space station surfaces, negative ionization

2024-01-05 | MSV000093782 | GNPS

GNPS - 3D mapping of the International Space Station positive ionization

Project description:Surface swab samples from the International Space Station. Extracted with EtOH/H2O 50/50. Analyzed with 5 cm C18 column 10 minuates gradient elution. Internal standard Sulfadimethoxine-d5.

2024-02-29 | MSV000094202 | GNPS

GNPS - 3D mapping of the International Space Station negative ionization

2024-02-29 | MSV000094203 | GNPS

GNPS - International Space Station 3DMM

Project description:803 surface swabs from Internation Space Station. Dry swab extracted with ACN/H2O 1:1.

2022-08-05 | MSV000090086 | GNPS

Validation of a novel diagnostic standard in HPV-positive oropharyngeal squamous cell carcinoma.

Project description:Human papillomavirus (HPV) testing in oropharyngeal squamous cell carcinoma (OPSCC) is now advocated. Demonstration of transcriptionally active high-risk HPV (HR-HPV) in fresh tumour tissue is considered to be the analytical 'gold standard'. Clinical testing has focused on formalin-fixed paraffin-embedded (FFPE) tissue at the expense of sensitivity and specificity. Recently, a novel RNA in situ hybridisation test (RNAscope) has been developed for the detection of HR-HPV in FFPE tissue; however, validation against the 'gold standard' has not been reported.A tissue microarray comprising FFPE cores from 79 OPSCC was tested using HR-HPV RNAscope. Analytical accuracy and prognostic capacity were established by comparison with the reference test; qRT-PCR for HR-HPV on matched fresh-frozen samples.High-risk HPV RNAscope had a sensitivity and specificity of 97 and 93%, respectively, against the reference test. Kaplan-Meier estimates of disease-specific survival (DSS, P=0.001) and overall survival (OS, P<0.001) by RNAscope were similar to the reference test (DSS, P=0.003, OS, P<0.001) and at least, not inferior to p16 immunohistochemistry +/- HR-HPV DNA-based tests.HR-HPV RNAscope demonstrates excellent analytical and prognostic performance against the 'gold standard'. These data suggest that the test could be developed to provide the 'clinical standard' for assigning a diagnosis of HPV-related OPSCC.

| S-EPMC3619267 | biostudies-other

Microgravity effect on C. elegans N2/VC (CERISE, 8days)

Project description:Microgravity effect on C. elegans gene expression was analysed by whole genome microarray. The worms were cultivated under microgravity for 8days in the Japanese Module of the International Space Station.

2012-06-30 | GSE27338 | GEO

Microgravity effect on C. elegans N2/VC (CERISE, 4 days)

Project description:Microgravity effect on C. elegans gene expression was analysed by whole genome microarray. The worms were cultivated under microgravity for 4 days in the Japanese Module of the International Space Station.

2016-08-31 | GSE71770 | GEO