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Plasma proteomics analysis of adolescent idiopathic scoliosis patients revealed by Quadrupole-Orbitrap Mass Spectrometry

ABSTRACT: We aim to investigate the changes of plasma proteome among mild, severe AIS patients and healthy controls.

ORGANISM(S): Homo Sapiens

SUBMITTER: Xuesong Zhang

PROVIDER: PXD024246 | iProX | Thu Feb 18 00:00:00 GMT 2021

REPOSITORIES: iProX

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Plasma proteomics analysis of adolescent idiopathic scoliosis patients revealed by Quadrupole-Orbitrap mass spectrometry.

Wang Qi Q Wang Chi C Liu Jiayu J Sun Jingru J Wang Chengbin C Zhang Xuesong X

Proteomics. Clinical applications 20210513 4

<h4>Objective</h4>We aim to investigate the changes of plasma proteome among mild, severe adolescent idiopathic scoliosis (AIS) patients and healthy controls.<h4>Methods</h4>In this retrospective study, there were 84 individuals including 56 confirmed AIS patients (27 follow-up AIS patients and 29 surgical AIS patients) and another 28 healthy teenagers. Plasma samples were obtained and Quadrupole-Orbitrap Mass Spectrometer was performed to identify proteins in AIS patients and control group. T-t ...[more]

PMID: 33864425

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