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Molecular basis of nuclear mRNA recognition and packaging

ABSTRACT: Newly made messenger RNAs are processed and packaged into compact ribonucleoprotein complexes (mRNPs) and recognized by the essential transcription-export complex (TREX) for nuclear export. However, the mechanisms of mRNP recognition, compaction, and three-dimensional organization are poorly understood. Here we perform crosslinking MS on Sulfo-SDA crosslinked endogenous ribonucleoprotein complexes (mRNPs). These have been enriched through a pulldown of THOC1-3C-GFP.

ORGANISM(S): Homo Sapiens (human)

SUBMITTER: Juri Rappsilber

PROVIDER: PXD031755 | JPOST Repository | Tue Jan 31 00:00:00 GMT 2023

REPOSITORIES: jPOST

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			Action	DRS
	recal_B210403_03_Lumos_FO_CO_Plaschka_endoTHO_SDA_pepSEC5.mgf	Mgf
	recal_B210403_04_Lumos_FO_CO_Plaschka_endoTHO_SDA_pepSEC6.mgf	Mgf
	recal_B210403_05_Lumos_FO_CO_Plaschka_endoTHO_SDA_pepSEC7.mgf	Mgf
	recal_B210403_06_Lumos_FO_CO_Plaschka_endoTHO_SDA_pepSEC8.mgf	Mgf
	recal_B210403_07_Lumos_FO_CO_Plaschka_endoTHO_SDA_pepSEC9.mgf	Mgf

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