Dataset Information

IPRG 2012: A Study on Detecting Modified Peptides in a Complex Mixture

ABSTRACT: This is the data and results associated with the 2012 study organized by the proteome informatics research group of the Association of Biomolecular Resource Facilities, which investigated participants' ability to identify a range of post-translationally modified peptides spiked into a yeast lysate background. Results and analysis of this study were published in Molecular and Cellular Proteomics: Chalkley RJ, Bandeira N, Chambers MC, Clauser K, Cottrell J, Deutsch EW, Kapp EA, Lam HH, McDonald WH, Neubert TA, Sun RX Mol Cell Proteomics 2013 [Epub Oct 31]

INSTRUMENT(S): TripleTOF 5600

ORGANISM(S): Saccharomyces Cerevisiae (ncbitaxon:4932)

SUBMITTER: Robert Chalkley

PROVIDER: MSV000078492 | MassIVE | Tue Nov 19 16:45:00 GMT 2013

REPOSITORIES: MassIVE

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Proteome informatics research group (iPRG)_2012: a study on detecting modified peptides in a complex mixture.

Chalkley Robert J RJ Bandeira Nuno N Chambers Matthew C MC Clauser Karl R KR Cottrell John S JS Deutsch Eric W EW Kapp Eugene A EA Lam Henry H N HH McDonald W Hayes WH Neubert Thomas A TA Sun Rui-Xiang RX

Molecular & cellular proteomics : MCP 20131031 1

The proteome informatics research group of the Association of Biomolecular Resource Facilities conducted a study to assess the community's ability to detect and characterize peptides bearing a range of biologically occurring post-translational modifications when present in a complex peptide background. A data set derived from a mixture of synthetic peptides with biologically occurring modifications combined with a yeast whole cell lysate as background was distributed to a large group of research ...[more]

PMID: 24187338

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