Proteomics

Dataset Information

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Detergent Resistant Memebrane Proteome of Plasmodium Berghei trophozoites and gametocytes


ABSTRACT: Proteomic characterization of complexity and dynamics of detergent resistant membranes of sexual and asexual stages of the rodent malaria parasite Plasmodium berghei

INSTRUMENT(S): LTQ XL ETD

ORGANISM(S): Plasmodium Berghei Anka (ncbitaxon:5823)

SUBMITTER: FEDERICA FRATINI  

PROVIDER: MSV000080108 | MassIVE | Wed Aug 31 09:44:00 BST 2016

REPOSITORIES: MassIVE

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Publications

An Integrated Approach to Explore Composition and Dynamics of Cholesterol-rich Membrane Microdomains in Sexual Stages of Malaria Parasite.

Fratini Federica F   Raggi Carla C   Sferra Gabriella G   Birago Cecilia C   Sansone Anna A   Grasso Felicia F   Currà Chiara C   Olivieri Anna A   Pace Tomasino T   Mochi Stefania S   Picci Leonardo L   Ferreri Carla C   Di Biase Antonella A   Pizzi Elisabetta E   Ponzi Marta M  

Molecular & cellular proteomics : MCP 20170810 10


Membrane microdomains that include lipid rafts, are involved in key physiological and pathological processes and participate in the entry of endocellular pathogens. These assemblies, enriched in cholesterol and sphingolipids, form highly dynamic, liquid-ordered phases that can be separated from the bulk membranes thanks to their resistance to solubilization by nonionic detergents. To characterize complexity and dynamics of detergent-resistant membranes of sexual stages of the rodent malaria para  ...[more]

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