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Chemical proteomic map of dimethyl fumarate-sensitive cysteines in primary human T cells

ABSTRACT: Primary human and mouse T cells were treated with the multiple sclerosis drug dimethyl fumarate (DMF) or its in vivo metabolite monomethyl fumarate (MMF). Cysteines sensitive to DMF or MMF were identified using iodoacetamide alkyne enrichment.

INSTRUMENT(S): LTQ Orbitrap Velos

ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Mus Musculus (ncbitaxon:10090)

SUBMITTER: Benjamin Cravatt

PROVIDER: MSV000080111 | MassIVE | Wed Aug 31 17:23:00 BST 2016

REPOSITORIES: MassIVE

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