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Glutaminolysis fuels de novo glutathione synthesis, regulates redox homeostasis and directs T cell differentiation

ABSTRACT: We reveal that dimethyl fumarate, a FDA approved drug (BG-12/Tecfidera) for multiple sclerosis, suppresses TH17 differentiation by augmenting intracellular ROS

ORGANISM(S): Mus musculus

PROVIDER: GSE98733 | GEO | 2018/05/01

REPOSITORIES: GEO

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