Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Autosampler testing -EHP

ABSTRACT: DOI: 10.1007/s00216-016-0122-8 Evaluation of PrinCE autosampler

INSTRUMENT(S): QE-HF

ORGANISM(S): Xenopus <genus> (ncbitaxon:8353)

SUBMITTER: Norman J. Dovichi

PROVIDER: MSV000081688 | MassIVE | Wed Nov 08 04:59:00 GMT 2017

REPOSITORIES: MassIVE

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

Sample Prep -EHP

Project description:doi: 10.1007/s00216-016-9564-2 All data was ran and analyzed at ND.

2017-11-08 | MSV000081691 | MassIVE

Analysis of colorectal adenocarcinoma tissue samples by DESI mass spectrometry imaging

Project description:Ex vivo colorectal adenocarcinoma samples were analysed by desorption electrospray ionisation using an Orbitrap mass spectrometer. The samples were analysed in negative mode over the m/z range 600-1000. Some of the samples presented in this dataset were analysed as part of [1]. The study makes available imzML files of profile and centroid mode data, as well as low- and high- resolution optical image files of H&E-stained sections. These files can be found in the zip file named after each tissue section. Ref: [1] Gerbig S, Golf O, Balog J, Denes J, Baranyai Z, Zarand A, Raso E, Timar J, Takats Z. Analysis of colorectal adenocarcinoma tissue by desorption electrospray ionization mass spectrometric imaging. Anal Bioanal Chem. 2012 Jun;403(8):2315-25. doi:10.1007/s00216-012-5841-x. PMID:22447214

2016-04-28 | MTBLS289 | MetaboLights

Expression profiling of Fusarium oxysporum infected wild-type Arabidopsis and a 35S Fusarium SIX4 overexpression line.

Project description:Fungal effectors play important roles in inciting disease development on host plants. We identified an effector (Secreted in Xylem4, SIX4) in an Arabidopsis infecting isolate (Fo5176) of the root-infecting fungal pathogen Fusarium oxysporum and demonstrated this effector is required for full virulence. To explore the role of Fo5176_SIX4 we use whole transcriptome profiling of root tissues from plants overexpressing this effector (35sSIX4) versus wild-type (Col-0) plants after F. oxysporum infection. Published in DOI:10.1007/978-3-319-42319-7_4. Belowground Defence Strategies in Plants.

2016-05-31 | GSE75928 | GEO

Transcription profiling by microarray of mouse B16F10 cells transduced with cDNAs encoding eGFP control, p19Arf, murine interferon-beta (IF-B) or the combination of p19Arf plus IF-B to study the modulated genes

Project description:Taking the advantage that B16F10 cells retain the wild-type p53, we introduced the p53 partner into these cells, the p19Arf. Also, in order to induce a immune stimulation in experiments *in vivo*, we introduced the interferon-beta cDNA. This combination induced several benefits when compared to the use of these factors alone, as seen by propidium iodide staining, tunel staining, several gene expression analysis, tumor growth, mice survival, among others. Because of this, we had the interest to study the effects of the combination of p19Arf plus interferon-beta upon gene regulation of B16F10 cells, compared to the effects of these transgenes alone. Previous works from our group that show several benefits of p19Arf plus interferon-beta combination upon B16F10 cells are described in Merkel et al (2010) doi: 10.1186/1471-2407-10-316, Merkel et al (2013) doi:10.1038/cgt.2013.23 and Medrano et al (2016) doi: 10.1007/s00262-016-1807-8 .

2017-12-02 | E-MTAB-5399 | biostudies-arrayexpress

Astrocyte proteome from the rat substantia nigra. Study in animal model of fluorocitrate-induced astrocyte dysfunction and microglia activation.

Project description:Dysfunction of astrocytic support for prolonged time can be harmful for nervous system. Inflammation and glia activation are among hallmarks of most neurodegenerative diseases. Therefore, astrocytes are considered as druggable targets for disease modifying strategies. Partial lesion of dopaminergic neurons is compensated functionally, but which mechanisms within each type of cells are responsible is unknown. The aim was to check how neuron vs astrocyte degeneration affected remaining astrocytes proteome and which mechanisms were regulated. In a rat model of 7-day infusion by osmotic minipumps of fluorocitrate (FC) into the substantia nigra (SN) (doi: 10.1007/s12035-017-0529-z; doi: 10.1111/jnc.14605; doi: 10.1016/j.mito.2018.12.002) astrocytes become dysfunctional and die inducing activation of remaining astrocytes and microglia. 6-OHDA injected into medial forebrain bundle caused selective degeneration of dopaminergic neurons in the SN. Controls were sham operated. Astrocytes were sorted out from dissociated SN tissue using FACS, and processed for mass spectrometry proteome analysis. Understanding the role of individual cell type in the diseased tissue cellular context is essential to understand disease pathomechanisms and identify better pharmacological targets.

2026-02-11 | PXD067265 | Pride

Investigation of conditions (type/amount of N fertilizer, pH of soil) influencing BNI exudation

Project description:Soil cultivation of spring wheat cultivar Remus. Hydroponic sampling of exudates to search for the BNI MBOA (and related compounds) Quantify MBOA Search for other known BNIS Characterize exudate LC-HRMS according to 10.1007/s00216-025-05818-y

2026-01-08 | MSV000100411 | MassIVE

Microglia proteome from the rat substantia nigra. Study in animal model of fluorocitrate-induced astrocyte dysfunction and microglia activation.

Project description:Nervous system inflammation and microglia activation are among hallmarks of Parkinson’s disease. Partial nigrostriatal neurodegeneration can be compensated. Interaction between neurons, microglia and astrocytes could be essential for this functional adaptation and neuronal survival in long-term, but which mechanisms are responsible is unknown. The aim was to check how astrocyte vs neuron degeneration affected differentially microglia activation proteome and which mechanisms were regulated. In a rat model of 7-day infusion by osmotic minipumps of fluorocitrate (FC) into the substantia nigra (SN) (doi: 10.1007/s12035-017-0529-z; doi: 10.1111/jnc.14605; doi: 10.1016/j.mito.2018.12.002) astrocytes become dysfunctional and die, strongly activating microglia in the process. 6-OHDA injected into medial forebrain bundle caused selective degeneration of dopaminergic neurons in the SN and only slightly activated microglia, probably via different mechanism. Controls were sham operated. Microglia cells were sorted out from dissociated SN tissue using FACS, and processed for mass spectrometry proteome analysis. Microglial response to dying astrocytes vs dying neurons was different. Understanding the role of individual cell type in the diseased tissue cellular context is essential to understand disease pathomechanisms and identify better pharmacological targets.

2026-02-11 | PXD066353 | Pride

MBOA in root exudates (and leachates) of winter/summer/mixed wheat cultivars

Project description:Soil cultivation of 11 winter/summer/mixed wheat cultivars. Collection of irrigation water (leachates). Hydroponic sampling of exudates to search for the BNI MBOA (and related compounds) Aims: - Quantify MBOA - Search for other known BNIS - Characterize exudate LC-HRMS according to 10.1007/s00216-025-05818-y

2026-01-08 | MSV000100410 | MassIVE

RRBS (DNA methylation) analysis of CD4+ CD8+ and CD4-CD8- fractions of PBMC cells collected from 7 case children, who were positive for type 1 diabetes specific autoantibodies, and their matched controls, sampled at 3, 6, 12, 18, 24, and 36 months of age

Project description:10.1007/s00125-022-05657-x

2022-02-14 | E-MTAB-11088 | biostudies-arrayexpress

Enteric adenovirus antibody reactivity in year-1 infant serum measured using a protein microarray

Project description:Processed and raw enteric adenovirus protein microarray reactivity data from 119 year-1 infant serum samples from a Bangladeshi birth cohort, with sample-level metadata aligned to Table 1 of the associated manuscript (Hendrick J, et al. J Infect Dis. 2025; jiaf558. doi:10.1093/infdis/jiaf558).

2025-12-28 | GSE314977 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data