Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive
ORGANISM(S): Saccharomyces Cerevisiae (ncbitaxon:4932)
SUBMITTER: Aaron Johnson
PROVIDER: MSV000082363 | MassIVE | Tue May 15 21:11:00 BST 2018
SECONDARY ACCESSION(S): PXD009790
REPOSITORIES: MassIVE
Balas Maggie M MM Porman Allison M AM Hansen Kirk C KC Johnson Aaron M AM
Journal of proteome research 20180920 10
DNA packaged into chromatin is the core structure of the human genome. Nearly all eukaryotic genome regulation must interface with this genomic structure, and modification of the chromatin can influence molecular mechanisms that regulate the underlying DNA. Many processes are governed by regulated stepwise assembly mechanisms that build complex machinery on chromatin to license a specific activity such as transcription. Transcriptional activators drive the initial steps of gene expression, regul ...[more]