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Mouse Sperm TMT MCP

ABSTRACT: Mouse Sperm Proteomic Profiling - University of Newcastle - Dr. Matt Dun

INSTRUMENT(S): Q Exactive

ORGANISM(S): Mus Musculus (ncbitaxon:10090)

SUBMITTER: Dr. Matt Dun Brett Nixon

PROVIDER: MSV000082497 | MassIVE | Sun Jun 24 23:52:00 BST 2018

REPOSITORIES: MassIVE

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Publications

Proteomic Profiling of Mouse Epididymosomes Reveals their Contributions to Post-testicular Sperm Maturation.

Nixon Brett B De Iuliis Geoffry N GN Hart Hanah M HM Zhou Wei W Mathe Andrea A Bernstein Ilana R IR Anderson Amanda L AL Stanger Simone J SJ Skerrett-Byrne David A DA Jamaluddin M Fairuz B MFB Almazi Juhura G JG Bromfield Elizabeth G EG Larsen Martin R MR Dun Matthew D MD

Molecular & cellular proteomics : MCP 20180913 Suppl 1

The functional maturation of spermatozoa that is necessary to achieve fertilization occurs as these cells transit through the epididymis, a highly specialized region of the male reproductive tract. A defining feature of this maturation process is that it occurs in the complete absence of nuclear gene transcription or <i>de novo</i>, protein translation in the spermatozoa. Rather, it is driven by sequential interactions between spermatozoa and the complex external milieu in which they are bathed ...[more]

PMID: 30213844

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