Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

2 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 1000

Ancient DNA teeth

ABSTRACT: The data set contains MS/MS data on teeth extracts for Ancient DNA teeth samples ran in both positive and Negative ionization modes

INSTRUMENT(S): Q Exactive

ORGANISM(S): Homo Sapiens

SUBMITTER: Pieter Dorrestein

PROVIDER: MSV000083264 | MassIVE | Wed Dec 19 13:49:00 GMT 2018

REPOSITORIES: MassIVE

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	MSV000083264	Other

Items per page:

1 - 1 of 1

Similar Datasets

GNPS_Ancient DNA teeth

Project description:The data set contains MS/MS data on teeth extracts for Ancient DNA teeth samples ran in both positive and Negative ionization modes

2018-12-19 | MSV000083264 | GNPS

Protein Extraction from Ancient Teeth and Dental Calculus Compatible with Subsequent DNA Extraction

Project description:Dental calculus is becoming a crucial material in the study of past populations, with increasing interest in its proteomic and genomic content. Here we suggest further development of protocol for analysis of ancient proteins and a combined approach for subsequent ancient DNA extraction. We tested the protocol on recent teeth. We then applied the optimised protocol to ancient teeth to limit the destruction of calculus, as it is a precious and irreplaceable source of dietary, microbiological, and ecological information in the archaeological context. Finally, the applicability of the protocol was proven on samples of ancient calculus.

2023-09-11 | PXD042668 | Pride

No ancient pathogen DNA in petrous bones

Project description:Ancient pathogen DNA in human teeth and petrous bones

| PRJEB24937 | ENA

Minimally Destructive DNA Extraction from Ancient Teeth

Project description:A Minimally Destructive Protocol for DNA Extraction from Ancient Teeth

| PRJEB32750 | ENA

An ancient protein-DNA interaction underlying metazoan sex determination

Project description:Sexual reproduction is nearly universal among multicellular animals, but sex can be determined by cues including sex chromosomes, temperature, social status, and photoperiod. DMRT transcription factors are key regulators of sex in animals that use diverse sex-determining strategies. These proteins are related to the sexual regulators Doublesex (Dsx) and Male abnormal-3 (MAB-3) of insects and nematodes, respectively. DMRT proteins share the DM DNA binding domain, comprised of a unique intertwined double zinc-binding module flanked by a C-terminal recognition helix that binds to a pseudopalindromic target DNA. Despite the central role of DMRT proteins in metazoan sexual development, how they recognize target DNA sequences is poorly understood. Here we find that DMRT proteins employ multiple DNA binding modes due to surprising versatility in how specific base contacts are made. Human DMRT1 can bind as a dimer, trimer or tetramer, in each case using paired antiparallel recognition helices that together insert into a widened DNA major groove to make base-specific contacts. Insertion of two helices in a single major groove is, to our knowledge, a DNA binding interaction unique to DMRT proteins. High resolution in vivo DNA binding analysis (ChIP-Exo) indicates that multiple DNA binding modes also are used in the mouse testis. Finally, we show that mutations affecting amino acid residues crucial for DNA recognition are associated with sex reversal in flies and also, for the first time, with male-to-female sex reversal in humans. Our results illuminate an ancient molecular interaction that underlies much of metazoan sexual development.

2015-05-18 | GSE64892 | GEO

Ancient Oral Pathogens Identified in Viking Teeth

Project description:Ancient Oral Pathogens Identified in Viking Teeth

| PRJEB75954 | ENA

Paleoproteomics of ancient human teeth

Project description:Teeth are a well-known source of information for paleoanthropologists. Here, we established the ancient dental metaproteomes in several samples from historic sites. The shotgun metaproteomics analysis relies on a iterative search strategy for the identification of the proteins and their origins.

2023-03-30 | PXD031786 | Pride

Extended paleoproteomics of ancient human teeth

2023-03-30 | PXD031802 | Pride

CT-scan ancient DNA

Project description:Optimized DNA sampling of ancient bones using Computed Tomography (CT) scans

| PRJEB25493 | ENA

Ancient DNA hyRAD capture

Project description:Performance and automation of ancient DNA capture with RNA hyRAD probes.

| PRJEB43744 | ENA