Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive
ORGANISM(S): Mus Musculus (ncbitaxon:10090)
SUBMITTER: Pingsheng Liu
PROVIDER: MSV000084105 | MassIVE | Wed Jul 17 23:34:00 BST 2019
SECONDARY ACCESSION(S): PXD014224
REPOSITORIES: MassIVE
Liu Qingfeng Q Zhou Ziyun Z Liu Pingsheng P Zhang Shuyan S
FEBS letters 20190712 16
Laboratory mice are standardly housed at around 23 °C, setting them under chronic cold stress. Metabolic changes in the liver in mice housed at thermoneutral, standard and cold temperatures remain unknown. In the present study, we isolated lipid droplets and mitochondria from their livers in a comparative proteomic study aiming to investigate the changes. According to proteomic analysis, mitochondrial tricarboxylic acid cycle (TCA cycle) and retinol metabolism are enhanced, whereas oxidative pho ...[more]