Changes in the ECM during mouse kidney development
Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive HF
ORGANISM(S): Mus Musculus (ncbitaxon:10090)
SUBMITTER: 
Sarah Calve
PROVIDER: MSV000085616 | MassIVE | Sun Jun 21 15:05:00 BST 2020
REPOSITORIES: MassIVE
Publications
3D Mapping Reveals a Complex and Transient Interstitial Matrix During Murine Kidney Development.
Lipp Sarah N SN Jacobson Kathryn R KR Jacobson Kathryn R KR Hains David S DS Schwarderer Andrew L AL Calve Sarah S
Journal of the American Society of Nephrology : JASN 20210419 7
<h4>Background</h4>The extracellular matrix (ECM) is a network of proteins and glycosaminoglycans that provides structural and biochemical cues to cells. In the kidney, the ECM is critical for nephrogenesis; however, the dynamics of ECM composition and how it relates to 3D structure during development is unknown.<h4>Methods</h4>Using embryonic day 14.5 (E14.5), E18.5, postnatal day 3 (P3), and adult kidneys, we fractionated proteins based on differential solubilities, performed liquid chromatogr ...[more]
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