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Schizophrenia Proteome Data High Resolution Method

ABSTRACT: PTM-tolerant quantitative proteome analysis of plasma collected from schizophrenia patients and nonspychiatric healthy controls.

INSTRUMENT(S): Orbitrap Fusion

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

SUBMITTER: David Gonzalez

PROVIDER: MSV000086977 | MassIVE | Tue Mar 02 15:36:00 GMT 2021

SECONDARY ACCESSION(S): PXD024474

REPOSITORIES: MassIVE

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Publications

Multi-omics of human plasma reveals molecular features of dysregulated inflammation and accelerated aging in schizophrenia.

Campeau Anaamika A Mills Robert H RH Stevens Toer T Rossitto Leigh-Ana LA Meehan Michael M Dorrestein Pieter P Daly Rebecca R Nguyen Tanya T TT Gonzalez David J DJ Jeste Dilip V DV Hook Vivian V

Molecular psychiatry 20211105 2

Schizophrenia is a devastating psychiatric illness that detrimentally affects a significant portion of the worldwide population. Aging of schizophrenia patients is associated with reduced longevity, but the potential biological factors associated with aging in this population have not yet been investigated in a global manner. To address this gap in knowledge, the present study assesses proteomics and metabolomics profiles in the plasma of subjects afflicted with schizophrenia compared to non-psy ...[more]

PMID: 34741130

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