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Child et al SRPR Data Set_SILAC_TMT

ABSTRACT: Here we utilized CRISPR/Cas9 editing and RNAi to disable SR protein expression in HeLa cells. Loss of SR heterodimer expression was confirmed by SILAC proteomic analyses in HeLa Cas9 parental and SR-deficient cells. These studies also demonstrated that the membrane protein proteome was largely unaltered by loss of SR, though reduced expression of a limited subset of membrane proteins was observed.

INSTRUMENT(S): Q Exactive HF-X

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

SUBMITTER: Dr. Christopher Nicchitta

PROVIDER: MSV000087992 | MassIVE | Mon Aug 16 15:43:00 BST 2021

REPOSITORIES: MassIVE

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