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Activation of Histone 3 Lysine 9 methyl writing and reading capabilities within the G9a-GLP heterodimer


ABSTRACT: BS3 Crosslinking experiments were performed on in vitro preparations of histone methyltransferase dimers. Each sample was fractionated into two size-exclusion chromatography fractions that were acquired by alternating HCD/EThcD scans of the same precursor on a Fusion-Lumos instrument. File mappings: GLP homodimer, SEC1: Z20210712-08 GLP homodimer, SEC2: Z20210712-09 G9a homodimer, SEC1: Z20210712-10 GLP homodimer, SEC2: Z20210712-11 G9aGLP heterodimer, SEC1: Z20210712-12 G9aGLP heterodimer, SEC2: Z20210712-13

INSTRUMENT(S): Orbitrap Fusion Lumos

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

SUBMITTER: Bassem Al-Sady  

PROVIDER: MSV000088143 | MassIVE | Wed Sep 22 14:41:00 BST 2021

REPOSITORIES: MassIVE

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