Proteomics

Dataset Information

0

Proteomic-based identification of APCS as candidate protein for diagnosis of patients exhibiting Anti-tubercular drug induced liver injury

ABSTRACT: In the present study, the proteomics approach identified potential protein signatures with high discriminative ability in TB patients with and without drug-induced liver injury which might play a crucial role in developing Anti-tubercular drug-induced liver injury.

INSTRUMENT(S): Orbitrap Fusion

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

SUBMITTER: Sadhna Sharma  

PROVIDER: MSV000088373 | MassIVE | Fri Nov 12 10:20:00 GMT 2021

REPOSITORIES: MassIVE

Json Xml

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1
altmetric image

Publications

Proteomic-based identification of APCS as candidate protein for diagnosis of patients exhibiting anti-tubercular drug induced liver injury.

Kaur Bhavneet B   Dixit Ravi R   Bakshi Shikha S   Konar Monidipa M   Sinha Saroj K SK   Duseja Ajay Kumar AK   Sharma Sadhna S  

Scientific reports 20230622 1

Traditional markers evaluate anti-tubercular drug-induced liver injury (AT-DILI). However, these markers have certain limitations and studies are in progress to characterize AT-DILI at an early stage. In the present study, 40 patients were categorized and equally distributed into healthy controls, newly diagnosed tuberculosis (TB), TB without hepatotoxicity and TB with hepatotoxicity groups based on their conventional liver function tests. Relative protein quantification was performed on deplete  ...[more]

Similar Datasets

Genomics Small RNAs in anti-tuberculosis drug-induced liver injury
2023-12-25 | GSE146260 | GEO
Genomics Drug-Induced Liver Injury (DILIN) GWAS
| PRJNA219213 | ENA
Genomics Small RNAs in anti-tuberculosis drug-induced liver injury
| PRJNA609915 | ENA
Genomic NIDDK Drug-Induced Liver Injury Network (DILIN)
| phs000663 | dbGaP
Methylation profiling Genome-wide methylation analysis in Anti-tuberculosis Drug Induced Liver Injury case and control samples
2021-12-24 | GSE124415 | GEO
Transcriptomics Expression data in sera from patients with anti-tuberculosis drug-induced liver injury
2021-01-01 | GSE141362 | GEO
Transcriptomics The role of corticosterone in nevirapine-induced idiosyncratic drug-induced liver injury
2024-04-15 | GSE255038 | GEO
Genomics Expression data in sera from patients with anti-tuberculosis drug-induced liver injury
| PRJNA593211 | ENA
Genomics Polygenic architecture informs potential vulnerability to drug-induced liver injury
| PRJNA639439 | ENA
Genomics The role of corticosterone in nevirapine-induced idiosyncratic drug-induced liver injury
| PRJNA1073404 | ENA