Transcriptomics

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Expression data in sera from patients with anti-tuberculosis drug-induced liver injury


ABSTRACT: The pathogenesis of liver damage induced by anti-tuberculosis drugs is not fully understood, andcurrently, there is no clinically useful biomarker for early diagnosis and treatment.By comparing the differences in the expression of global gene transcripts in the serum of patients with and without anti-tuberculosis drugs induced liver injury, dysregulation genes not only provides a basis for studying pathogenesis, but also provides important information to find new targets for diagnosis and treatment of disease. We used microarrays to detail the global programme of gene expression in sera underlying anti-tuberculosis drug-induced liver injury and identified distinct classes of transcript during this process.

ORGANISM(S): Homo sapiens

PROVIDER: GSE141362 | GEO | 2021/01/01

REPOSITORIES: GEO

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