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A naturally occurring variant of SHLP2 is a protective factor in Parkinson disease

ABSTRACT: Although mitochondrial DNA single nucleotide polymorphisms have been associated with Parkinsons disease their functional effects are unclear. Here, we functionalized a PD-associative mtSNP and found that it affects a mitochondrial-derived peptide MDP.

INSTRUMENT(S): Q Exactive Plus

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

SUBMITTER: Pinchas Cohen

PROVIDER: MSV000089632 | MassIVE | Sat Jun 11 11:24:00 BST 2022

SECONDARY ACCESSION(S): PXD034482

REPOSITORIES: MassIVE

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