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Proteomic analysis indicates that Cav-1 regulates mitochondria and cellular metabolism pathways in hippocampal NSPCs

ABSTRACT: To investigate the mechanisms underlying Cav-1 regulation of NSPCs, we used quantitative proteomics to assess protein alterations in response to Cav-1 deletion in primary hippocampal NSPCs. Due to our findings that Cav-1 deletion in NSPCs reduces proliferation, we hypothesized that Cav-1 regulates proteins and pathways involved cell cycle dynamics and proliferation.

INSTRUMENT(S): Q Exactive

ORGANISM(S): Mus Musculus (ncbitaxon:10090)

SUBMITTER: Stephanie Cologna

PROVIDER: MSV000090289 | MassIVE |

REPOSITORIES: MassIVE

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