Dataset Information

The influence of iron availability on protein carbonylation in Arabidopsis thaliana plant

ABSTRACT: The study examined the proteins that were specifically carbonylated in the wild-type seedlings exposed to iron-deficiency conditions. The results indicated that proteins were differentially carbonylated between the wild type and the triple ferritin mutant Fer1-3-4 in the leaves, stem, and flowers in either control or heat stress conditions. A change in the iron availability in the growth medium greatly influenced the carbonylation of certain proteins involved in the intracellular signal transduction, translation, and iron-deficiency response. Overall, the study underlined the importance of iron homeostasis in the occurrence of protein carbonylation in vivo.

INSTRUMENT(S): Orbitrap Fusion

ORGANISM(S): Arabidopsis Thaliana (ncbitaxon:3702)

SUBMITTER: Tagnon Missihoun

PROVIDER: MSV000090535 | MassIVE | Fri Oct 14 13:46:00 BST 2022

SECONDARY ACCESSION(S): PXD037445

REPOSITORIES: MassIVE

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Iron Availability Influences Protein Carbonylation in <i>Arabidopsis thaliana</i> Plants.

Tola Adesola J AJ Missihoun Tagnon D TD

International journal of molecular sciences 20230604 11

Protein carbonylation is an irreversible form of post-translational modification triggered by reactive oxygen species in animal and plant cells. It occurs either through the metal-catalyzed oxidation of Lys, Arg, Pro, and Thr side chains or the addition of α, β-unsaturated aldehydes and ketones to the side chains of Cys, Lys, and His. Recent genetic studies concerning plants pointed to an implication of protein carbonylation in gene regulation through phytohormones. However, for protein carbonyl ...[more]

PMID: 37298684

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