Ontology highlight
ABSTRACT:
INSTRUMENT(S): QExactive
ORGANISM(S): Homo Sapiens (ncbitaxon:9606)
SUBMITTER: Dr. Michael Ackerman
PROVIDER: MSV000091822 | MassIVE | Fri Apr 28 23:16:00 BST 2023
REPOSITORIES: MassIVE
Garmany Ramin R Bos J Martijn JM Tester David J DJ Giudicessi John R JR Dos Remedios Cristobal G CG Dasari Surendra S Nagaraj Nagaswaroop K NK Nair Asha A AA Johnson Kenneth L KL Ryan Zachary C ZC Maleszewski Joseph J JJ Ommen Steve R SR Dearani Joseph A JA Ackerman Michael J MJ
Circulation. Genomic and precision medicine 20230220 2
<h4>Background</h4>Hypertrophic cardiomyopathy (HCM) is characterized by asymmetric left ventricular hypertrophy. Currently, hypertrophy pathways responsible for HCM have not been fully elucidated. Their identification could serve as a nidus for the generation of novel therapeutics aimed at halting disease development or progression. Herein, we performed a comprehensive multi-omic characterization of hypertrophy pathways in HCM.<h4>Methods</h4>Flash-frozen cardiac tissues were collected from gen ...[more]