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Plasmodium yoelii zygotes and female gametocytes

ABSTRACT: Plasmodium yoelii zygotes or female gametocytes were purified by FACS and analyzed by DIA LC-MS.

INSTRUMENT(S): Orbitrap Eclipse

ORGANISM(S): Plasmodium Yoelii (ncbitaxon:5861)

SUBMITTER: Kristian Swearingen

PROVIDER: MSV000092154 | MassIVE | Tue Jun 13 13:07:00 BST 2023

SECONDARY ACCESSION(S): PXD042955

REPOSITORIES: MassIVE

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Publications

Widespread release of translational repression across Plasmodium's host-to-vector transmission event.

Rios Kelly T KT McGee James P JP Sebastian Aswathy A Gedara Sanjaya Aththawala SA Moritz Robert L RL Feric Marina M Absalon Sabrina S Swearingen Kristian E KE Lindner Scott E SE

PLoS pathogens 20250108 1

Malaria parasites must respond quickly to environmental changes, including during their transmission between mammalian and mosquito hosts. Therefore, female gametocytes proactively produce and translationally repress mRNAs that encode essential proteins that the zygote requires to establish a new infection. While the release of translational repression of individual mRNAs has been documented, the details of the global release of translational repression have not. Moreover, changes in the spatial ...[more]

PMID: 39777415

Publication: 1/2

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