Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Untargeted UHPLC-MS/MS screen of human gut microbiome commensal isolate bacteria from healthy human donor feces and validated standards from 'Microbially-catalyzed conjugation of GABA and tyramine to bile acids'

ABSTRACT: Untargeted UPLC-MS/MS data from a screen of human gut microbiome commensal isolate bacteria from healthy human donor feces. Isolates include Mediterraneibacter gnavus MSK15.77 (NCBI accession NZ_JAAIRR010000000), Bacteroides ovatus MSK22.29 (NCBI accession NZ_JAHOCX010000000), Bifidobacterium longum DFI.2.45 (NCBI accession NZ_JAJCNS010000000), and Lachnoclostridium scindens SL.1.22 (NCBI accession GCA_020555615.1). The dataset includes validated bile acid standards. All using positive ionization.

INSTRUMENT(S): Orbitrap IQ-X (Thermo Scientific instrument model)

ORGANISM(S): Human Gut Microbiome Isolate Bacteria

SUBMITTER: Sean Crosson

PROVIDER: MSV000093035 | MassIVE | Wed Oct 04 10:49:00 BST 2023

REPOSITORIES: MassIVE

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

Untargeted UHPLC-MS/MS screen of healthy donor feces from 'Microbially-catalyzed conjugation of GABA and tyramine to bile acids'

Project description:Untargeted UPLC-MS/MS data from a screen of healthy donor feces. All using positive ionization.

2023-10-04 | MSV000093032 | MassIVE

Initial untargeted UHPLC-MS/MS screen from 'Microbially-catalyzed conjugation of GABA and tyramine to bile acids'

Project description:Untargeted UPLC-MS/MS data from the initial screen comparing B. fragilis P207 (NCBI accession NZ_CP114371) cultures with and without deoxycholic acid spike revealed gamma-aminobutyrodeoxycholic acid and tyraminodeoxycholic acid among other bile acid conjugates in spiked cultures. All using positive ionization.

2023-10-04 | MSV000093027 | MassIVE

Bile acid substrate specificity UHPLC-MS/MS screen from 'Microbially-catalyzed conjugation of GABA and tyramine to bile acids'

Project description:UPLC-MS/MS data from bile acid specificity screen comparing the ability of B. fragilis P207 (NCBI accession NZ_CP114371) to conjugate amines to deoxycholic acid, glycodeoxycholic acid, and cholic acid. All using positive ionization.

2023-10-04 | MSV000093029 | MassIVE

Isotopic labeling UHPLC-MS/MS bile acid amine conjugate confirmation from 'Microbially-catalyzed conjugation of GABA and tyramine to bile acids'

Project description:Bile acid amine conjugate identification by feeding of deoxycholic acid and isotope-labeled amine precursors to B. fragilis P207 (NCBI accession NZ_CP114371) followed by UHPLC-MS/MS analysis.

2023-10-04 | MSV000093028 | MassIVE

Untargeted UHPLC-MS/MS screen of pouchitis patient 207 feces from 'Microbially-catalyzed conjugation of GABA and tyramine to bile acids'

Project description:Untargeted UPLC-MS/MS data from a screen of pouchitis patient 207 feces across seven time points. All using positive ionization.

2023-10-04 | MSV000093031 | MassIVE

Normalized relative abundance measurement of amines in B. fragilis culture using GC-EI-MS with methoxyamine and TMS derivatization from 'Microbially-catalyzed conjugation of GABA and tyramine to bile acids'

Project description:Normalized relative abundance measurement of amines in B. fragilis P207 (NCBI accession NZ_CP114371) culture using GC-EI-MS with methoxyamine and TMS derivatization.

2023-10-04 | MSV000093030 | MassIVE

Extracellular miRNAs in serum and feces of mice exposed to high-dose radiation

Project description:Exposure to high-dose radiation causes life-threatening serious intestinal damage. Histological analysis is the most accurate method for judging the extent of intestinal damage after death. However, it is difficult to predict the extent of intestinal damage to body samples. Here we focused on extracellular microRNAs (miRNAs) released from cells and investigated miRNA species that increased or decreased in serum and feces using a radiation-induced intestinal injury mouse model. A peak of small RNA of 25–200 nucleotides was detected in mouse serum and feces 72 h after radiation exposure, and miRNA presence in serum and feces was inferred. MiRNAs expressed in the small intestine and were increased by more than 2.0-fold in serum or feces following a 10 Gy radiation exposure were detected by microarray analysis and were 4 in serum and 19 in feces. In this study, miR-375-3p, detected in serum and feces, was identified as the strongest candidate for a high-dose radiation biomarker in serum and/or feces using a radiation-induced intestinal injury model.

2023-12-15 | GSE247876 | GEO