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Synthetic confirmation of bile acid-amine conjugates from 'Microbially-catalyzed conjugation of GABA and tyramine to bile acids'

ABSTRACT: UPLC-MS/MS data used to confirm the retention times of bile acid conjugates to GABA and tyramine that were detected in microbial culture and human fecal samples. Synthesized conjugates included here are GABA-deoxycholic acid, tyramine-deoxycholic acid, GABA-cholic acid, tyramine-cholic acid, GABA-chenodeoxycholic acid, and tyramine-chenodeoxycholic acid. Data of biological samples (B. fragilis P207 spiked with DCA, healthy human donor 11 feces, patient 207 v12 feces) from the same UPLCMS/MS sequence is included for comparison and validation. All using positive ionization.

INSTRUMENT(S): Orbitrap IQ-X (Thermo Scientific instrument model)

ORGANISM(S): Bacteroides Fragilis P207

SUBMITTER: Sean Crosson

PROVIDER: MSV000093695 | MassIVE | Tue Dec 19 12:15:00 GMT 2023

REPOSITORIES: MassIVE

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