Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

NISTfecalRM_Astral_HypersilGoldC18_positive

ABSTRACT: NIST fecal reference material extracted with 50% MeOH and prepared in different dilutions and reconstitution solvents. The analysis was conducted using a Hypersil Gold (C18) in positive ionization mode on a Astral via different MS-modes (positive ionization mode).

INSTRUMENT(S): Orbitrap Astral

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

SUBMITTER: Pieter C Dorrestein

PROVIDER: MSV000093526 | MassIVE | Tue Nov 28 20:48:00 GMT 2023

REPOSITORIES: MassIVE

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

NISTfecalRM_Astral_HypersilGoldC18_negative

Project description:NIST fecal reference material extracted with 50% MeOH and prepared in different dilutions and reconstitution solvents. The analysis was conducted using a Hypersil Gold (C18) in negative ionization mode on a Astral via different MS-modes.

2023-11-28 | MSV000093527 | MassIVE

GNPS - NISTfecalRM_Astral_HypersilGoldC18_positive

Project description:NIST fecal reference material extracted with 50% MeOH and prepared in different dilutions and reconstitution solvents. The analysis was conducted using a Hypersil Gold (C18) in positive ionization mode on a Astral via different MS-modes (positive ionization mode).

2023-11-28 | MSV000093526 | GNPS

GNPS - NISTfecalRM_Astral_HypersilGoldC18_positive_2

Project description:NIST fecal reference material extracted with 50% MeOH and prepared in different dilutions and reconstitution solvents. The analysis was conducted using a Hypersil Gold (C18) in positive ionization mode on a Astral via different MS-modes.

2023-11-28 | MSV000093527 | GNPS

RNA-Seq on libraries made from serial dilutions of Drosophila melanogaster S2 cell mRNA and ERCC external RNA controls

Project description:RNA-Seq on libraries made from serial dilutions of mRNA from Drosophila melanogaster S2 cell and the External RNA Controls Consortium (ERCC) external RNA controls. We evaluated performance of RNA-Seq by serially diluting a complex pool of known synthetic PolyA+ mRNAs from the External RNA Controls Consortium (ERCC) and PolyA+ mRNA from Drosophila S2 cells. ERCC mRNAs were obtained under Phase V testing from the National Institutes of Standards and Technology (NIST). The ERCC pool contained 96 species of mRNA of various lengths and GC content covering a 2^20 concentration range. Libraries were constructed with 100ng to 10pg of input mRNA. Our data shows an outstanding linear fit between RNA-Seq read density and known input amounts.

2010-04-19 | GSE20555 | GEO

Gene expression profiling of macrophages: Implications for an immunosuppressive effect of dissolucytotic gold ions

Project description:Gold salts has been used in the treatment of rheumatoid arthritis but has been replaced by biologicals such as TNF-alpha inhibitors. The mechanisms behind the anti-inflammatory effect of metallic gold ions are still unknown, however, recent data showed that charged gold atoms are released from pure metallic gold implants by macrophages via a dissolucytosis membrane, and that gold ions are taken up by local macrophages, mast cells and to some extent fibroblasts. These current findings offer new treatment options for metallic gold and deeper understanding of the effect of metallic gold on key inflammatory cells as macrophages are essential. In the present study the impact of phagocytised gold ions on the global gene expression profile of the human monocytic cell line THP-1 was investigated, using microarray analysis comprising approximately 20,000 genes. The gene expression data was confirmed by measurement of three secreted proteins. A unique gene expression signature of dissolucytotic macrophages that had taken up gold ions was demonstrated. A large number of regulated genes were functionally related to immunomodulation/protection. Gold ion uptake into macrophages induced downregulation of central inflammatory cytokines as TNF-alpha, IL-32 and CD28. The data obtained in this study offer new insights into the mode of action of gold ions and suggest a future role of metallic gold as implants or topical applications in treating inflammation. To determine the effect of gold phagocytosis on global gene expression

2012-12-31 | E-GEOD-37814 | biostudies-arrayexpress

ASTRAL 15 and 30 min in-depth metaproteomics of a human fecal standard to evaluate depth of analysis following a taxonomical proteotyping strategy.

Project description:In-depth metaproteomics of a human fecal standard, MetaP, with ASTRAL tandem mass spectometer operated in data-independent acquisition mode for 15 min or 30 min and with a database built following sample taxonomical proteotyping.

2024-03-07 | PXD046290 | Pride

ASTRAL 60 and 90 min in-depth metaproteomics of a human fecal standard to evaluate depth of analysis following a taxonomical proteotyping strategy.

Project description:In-depth metaproteomics of a human fecal standard, MetaP, with ASTRAL tandem mass spectometer operated in data-independent acquisition mode for 60 min or 90 min and with a database built following sample taxonomical proteotyping.

2024-03-07 | PXD046320 | Pride

Gene expression profiling of macrophages: Implications for an immunosuppressive effect of dissolucytotic gold ions

2012-12-31 | GSE37814 | GEO

E.coli K-12 treated by IPL - analysis of polar phase (part-I)

Project description:E.coli K-12 cells were treated by IPL, extracted and separated into organic/lipid phase and polar phase. The polar phase was analyzed by HILIC-MS, in both positive and negative ionization mode.

2021-01-25 | ST001663 | MetabolomicsWorkbench

GNPS Streptomyces jumonjinensis NRRL 5741

Project description:Streptomyces jumonjinensis NRRL 5741 cultured on three different media, extracted with two different solvents, detected in both positive and negative ionization mode

2021-06-15 | MSV000087629 | GNPS

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data