Ho_BLM_TOP3A_RMI_BioID_P130_Velos_Elite
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ABSTRACT: This dataset consists of 25 raw MS files and associated peak lists and results files, acquired on a Thermo LTQ Velos Pro or Thermo Orbitrap Elite mass spectrometer operated in Data Dependent Acquisition mode.
Samples were generated by Edith Cheng. Affinity purifications and mass spectrometry acquisition was performed by Wade Dunham. Analysis was performed by Jennifer Ho, Wade Dunham, Edith Cheng, Cassandra Wong, Anne-Claude Gingras, and Grant Brown.
The files are associated with a manuscript submitted for publication by Jung Jennifer Ho et al. The main goal of this paper was to profile the proximity interactome of BLM-TOP3A-RMI1-RMI2 (BTRR) complex to identify proteins that suppress recombination in DNA repair. This dataset identifies the importance of RAD54L2 for the recruitment of Bloom (BLM) helicase to promote non-crossover recombination.
Grant W. Brown is the corresponding author of the manuscript (grant.brown@utoronto.ca); Anne-Claude Gingras should be contacted for questions on this dataset (gingras@lunenfeld.ca)
INSTRUMENT(S): LTQ Orbitrap Velos, LTQ Orbitrap Elite
ORGANISM(S): Homo Sapiens (ncbitaxon:9606)
SUBMITTER: Anne-Claude Gingras
PROVIDER: MSV000093876 | MassIVE | Tue Jan 16 10:24:00 GMT 2024
SECONDARY ACCESSION(S): PXD048612
REPOSITORIES: MassIVE
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