Proteomics

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Untargeted Blood Lipidomics Analysis in Critically Ill Pediatric Patients with Ventilator-Associated Pneumonia


ABSTRACT: Blood samples were collected from 20 patients with suspected ventilator-associated pneumonia (VAP), aged 6 months to 15 years, at days 1, 3, 6, and 12, followed by an untargeted lipidomics analysis using Ultra-High Pressure Liquid Chromatography coupled with High-Resolution Mass Spectrometry (UPLC-HRMS) on a TIMS-TOF/MS platform. Patients were stratified into high (mCPIS > 6, n = 12) and low (mCPIS < 6, n = 8) VAP suspicion groups based on the modified pediatric clinical pulmonary index score (mCPIS).

INSTRUMENT(S): timsTOF

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

SUBMITTER: Dr. Christina Virgiliou  

PROVIDER: MSV000097183 | MassIVE | Fri Feb 21 06:03:00 GMT 2025

REPOSITORIES: MassIVE

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