Untargeted Blood Lipidomics Analysis in Critically Ill Pediatric Patients with Ventilator-Associated Pneumonia
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ABSTRACT: Blood samples were collected from 20 patients with suspected ventilator-associated pneumonia (VAP), aged 6 months to 15 years, at days 1, 3, 6, and 12, followed by an untargeted lipidomics analysis using Ultra-High Pressure Liquid Chromatography coupled with High-Resolution Mass Spectrometry (UPLC-HRMS) on a TIMS-TOF/MS platform.
Patients were stratified into high (mCPIS > 6, n = 12) and low (mCPIS < 6, n = 8) VAP suspicion groups based on the modified pediatric clinical pulmonary index score (mCPIS).
INSTRUMENT(S): timsTOF
ORGANISM(S): Homo Sapiens (ncbitaxon:9606)
SUBMITTER:
Dr. Christina Virgiliou
PROVIDER: MSV000097183 | MassIVE | Fri Feb 21 06:03:00 GMT 2025
REPOSITORIES: MassIVE
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