Dataset Information

Discovery of A-type procyanidin dimers in yellow raspberries by untargeted metabolomics and correlation based data analysis

ABSTRACT: Introduction:
Raspberries are becoming increasingly popular due to their reported health beneficial properties. Despite the presence of only trace amounts of anthocyanins yellow varieties seems to show similar or better effects in comparison to conventional raspberries.
Objectives:
The aim of this work is to characterize the metabolic differences between red and yellow berries, focussing on the compounds showing a higher concentration in yellow varieties.
Methods:
The metabolomic profile of 13 red and 12 yellow raspberries (of different varieties, locations and collection dates) was determined by UPLC-TOF-MS and a novel correlation based approach was implemented to extract the pseudospectra of the most relevant biomarkers from high energy LC-MS runs.
Results:
Among the metabolites showing higher concentration in yellow raspberries it was possible to identify a series of compounds showing a pseudospectrum similar to that of A-type procyanidin polymers. The annotation of this group of compounds was confirmed by specific MS/MS experiments and performing standard injections.
Conclusion:
In berries lacking anthocyanins the polyphenol metabolism might be shifted to the formation of a novel class of A-type procyanidin polymers.

INSTRUMENT(S): SYNAPT HDMS (Waters)

SUBMITTER: Elisabete Carvalho

PROVIDER: MTBLS333 | MetaboLights | 2016-08-23

REPOSITORIES: MetaboLights

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Discovery of A-type procyanidin dimers in yellow raspberries by untargeted metabolomics and correlation based data analysis.

Carvalho Elisabete E Franceschi Pietro P Feller Antje A Herrera Lorena L Palmieri Luisa L Arapitsas Panagiotis P Riccadonna Samantha S Martens Stefan S

Metabolomics : Official journal of the Metabolomic Society 20160808 9

<h4>Introduction</h4>Raspberries are becoming increasingly popular due to their reported health beneficial properties. Despite the presence of only trace amounts of anthocyanins, yellow varieties seems to show similar or better effects in comparison to conventional raspberries.<h4>Objectives</h4>The aim of this work is to characterize the metabolic differences between red and yellow berries, focussing on the compounds showing a higher concentration in yellow varieties.<h4>Methods</h4>The metabol ...[more]

PMID: 27547172

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	MTBLS333	Other
	FILES	Other
	a_MTBLS333_metabolite_profiling_mass_spectrometry.txt	Txt
	i_Investigation.txt	Txt
	metexplore_mapping.json	Other