Metabolomics

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An Integrated Biochemical, Proteomics, and Metabolomics Approach for Supporting Medicinal Value of Panax ginseng Fruits (GC-MS assay)


ABSTRACT: Panax ginseng roots are well known for their medicinal properties and have been used in Korean and Chinese traditional medicines for 1000s of years. However, the medicinal value of P. ginseng fruits remain poorly characterized. Using gas chromatography-time of flight mass spectrometry (GC-TOF MS), 66 metabolites including amino acids, sugars, organic acids, phenolic acids, phytosterols, tocopherols, and policosanols were identified and quantified. Some of these are well known medicinal compounds and were not previously identified in ginseng. Interestingly, the concentration of almost all metabolites was higher in the Chunpoong and Gumpoong cultivars. Parallel comparison of the four cultivars also revealed higher amounts of the medicinal metabolites in Chunpoong and Gumpoong cultivars. Taken together, our results demonstrate that ginseng fruits are a rich source of medicinal compounds with potential beneficial health effects.

INSTRUMENT(S): Agilent 7890A GC-LECO Pegasus HT TOFMS

SUBMITTER: Sun Tae Kim 

PROVIDER: MTBLS350 | MetaboLights | 2016-11-18

REPOSITORIES: MetaboLights

Dataset's files

Source:
Action DRS
MTBLS350 Other
FILES Other
a_MTBLS350_ginseng_HYDRO_mass_spectrometry.txt Txt
a_MTBLS350_ginseng_LIPO_mass_spectrometry.txt Txt
i_Investigation.txt Txt
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Publications

An Integrated Biochemical, Proteomics, and Metabolomics Approach for Supporting Medicinal Value of Panax ginseng Fruits.

Kim So W SW   Gupta Ravi R   Lee Seo H SH   Min Cheol W CW   Agrawal Ganesh K GK   Rakwal Randeep R   Kim Jong B JB   Jo Ick H IH   Park Soo-Yun SY   Kim Jae K JK   Kim Young-Chang YC   Bang Kyong H KH   Kim Sun T ST  

Frontiers in plant science 20160704


Panax ginseng roots are well known for their medicinal properties and have been used in Korean and Chinese traditional medicines for 1000s of years. However, the medicinal value of P. ginseng fruits remain poorly characterized. In this study, we used an integrated biochemical, proteomics, and metabolomics approach to look into the medicinal properties of ginseng fruits. DPPH (1,1-diphenyl-2-picrylhydrazyl) and ABTS [2,2'-azino-bis (3-ethylbenzothiazoline-6-sulphonic acid)] assays showed higher a  ...[more]

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