Metabolomics

Dataset Information

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Drying Enhances Signal Intensities for Global GC–MS Metabolomics


ABSTRACT: We report here that a straightforward change of the standard derivatization procedure for GC–MS metabolomics is leading to a strong increase in metabolite signal intensity. Drying samples between methoxymation and trimethylsilylation significantly increased signals by two- to tenfold in extracts of yeast cells, plant and animal tissue, and human urine. This easy step reduces the cost of sample material and the need for expensive new hardware.

INSTRUMENT(S): Gas Chromatography MS - Positive (GC-MS (Positive))

SUBMITTER: Manuel Liebeke 

PROVIDER: MTBLS807 | MetaboLights | 2019-04-05

REPOSITORIES: MetaboLights

Dataset's files

Source:
Action DRS
MTBLS807 Other
FILES Other
a_MTBLS807_metabolite_profiling_mass_spectrometry.txt Txt
i_Investigation.txt Txt
m_MTBLS807_metabolite_profiling_mass_spectrometry_v2_maf.tsv Tabular
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