Ontology highlight
ABSTRACT:
INSTRUMENT(S): Liquid Chromatography MS - Alternating (LC-MS (Alternating))
SUBMITTER: Federica Giordani
PROVIDER: MTBLS882 | MetaboLights | 2022-01-18
REPOSITORIES: MetaboLights
Action | DRS | |||
---|---|---|---|---|
MTBLS882 | Other | |||
FILES | Other | |||
a_MTBLS882_mgb234_metabolite_profiling_mass_spectrometry-1.txt | Txt | |||
a_MTBLS882_mgb234_metabolite_profiling_mass_spectrometry.txt | Txt | |||
files-all.json | Other |
Items per page: 1 - 5 of 9 |
Journal of medicinal chemistry 20190313 6
Animal African trypanosomiasis (AAT) is a significant socioeconomic burden for sub-Saharan Africa because of its huge impact on livestock health. Existing therapies including those based on minor groove binders (MGBs), such as the diamidines, which have been used for decades, have now lost efficacy in some places because of the emergence of resistant parasites. Consequently, the need for new chemotherapies is urgent. Here, we describe a structurally distinct class of MGBs, Strathclyde MGBs (S-MG ...[more]