Metabolomics Approach to Allograft Assessment in Liver Transplantation (part II)
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ABSTRACT: This pilot study is designed to apply several types of metabolomic analysis for liver allograft assessment with the aim of identifying candidate biomarkers for allograft function and to develop a methodology that could be applied to larger scale studies. The three main categories of metabolomic analysis are reflected in each of the specific aims, including a targeted profiling of central carbon metabolism, open lipidomic and metabolomic profiling for hypothesis generation and MALDI-IMS for tissue-based spatial analysis. Each of these approaches offers potential benefits that could be optimized in a protocol for larger scale studies depending the results of the pilot investigations.
INSTRUMENT(S): Orbitrap
ORGANISM(S): Human Homo Sapiens
TISSUE(S): Liver
SUBMITTER: John Seal
PROVIDER: ST000424 | MetabolomicsWorkbench | Fri May 06 00:00:00 BST 2016
REPOSITORIES: MetabolomicsWorkbench
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