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Measuring acylcarnitine concentrations in insulin resistant and insulin deficient mouse tissue models

ABSTRACT: To compare models of insulin resistance to a model of loss of insulin signaling, we will also determine muscle acylcarnitine concentrations, using control and streptozotocin (STZ) treated mice as a model of insulin deficient diabetes. Changes in metabolite profiles will be correlated with activation of mTOR and FoxO pathways in muscle.

ORGANISM(S): Mouse Mus Musculus

TISSUE(S): Muscle

DISEASE(S): Diabetes

SUBMITTER: Brian O'Neill

PROVIDER: ST000517 | MetabolomicsWorkbench | Wed Dec 07 00:00:00 GMT 2016

REPOSITORIES: MetabolomicsWorkbench

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