Global metabolomics of human milk fractions
Ontology highlight
ABSTRACT: Pediatric obesity has more than doubled in children and tripled in adolescents over the past 30 years. Recent findings demonstrate that differences in energy harvesting bacteria promote obesity in the host and appear to be influenced by early life factors such as mode of delivery, maternal obesity, and breastfeeding. The goal of this proposal is to investigate how human milk impacts the infant gut microbiome during the first 12-months of life and identify the microbe-host interactions that mediates the protective role of breastfeeding on infant adiposity. The results of this exploratory study will characterize factors that influence microbial transmission between mothers and offspring and identify human milk compounds that stabilize a healthy infant microbiome with potential to reduce pediatric obesity.
ORGANISM(S): Human Homo Sapiens
TISSUE(S): Breast Milk
DISEASE(S): Obesity
SUBMITTER: Olivia Carney
PROVIDER: ST000957 | MetabolomicsWorkbench | Sun Apr 15 00:00:00 BST 2018
REPOSITORIES: MetabolomicsWorkbench
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