Metabolomics

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Untargeted lipidomics of liver to assess the potential protective role in atherosclerosis progression of A12 antibodies infusion into LDLR-/-mice


ABSTRACT: In order to assess the therapeutic potential of A12 antibodies in atherosclerosis, untargeted lipidomics of liver samples was performed. LDLR-/-mice were treated with a fully murine version of the A12 antibody (mA12-IgG2b), with the isotype control antibody mB1.8-IgG2b (n=16) or with PBS as controls.

ORGANISM(S): Mouse Mus Musculus

TISSUE(S): Liver

DISEASE(S): Atherosclerosis

SUBMITTER: Alessia Ferrarini  

PROVIDER: ST001434 | MetabolomicsWorkbench | Mon Jul 27 00:00:00 BST 2020

REPOSITORIES: MetabolomicsWorkbench

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